ZOLADEX 3.6MG DEPOT (goserelin) is a man-made form of a hormone that regulates many processes in the body. Goserelin overstimulates the body’s own production of certain hormones, which causes that production to shut down temporarily.

ZOLADEX 3.6MG DEPOT implants are used to treat symptoms of prostate cancer in men.

The Zoladex implant is used in women to treat breast cancer or endometriosis. Zoladex is also used in women to prepare the lining of the uterus for endometrial ablation (a surgery to correct abnormal uterine bleeding).

Zoladex is sometimes used in combination with another cancer drug called flutamide.

Goserelin can harm an unborn baby or cause birth defects. Unless you are being treated for advanced breast cancer, you should not use Zoladex during pregnancy. Use effective non-hormonal (barrier) birth control during treatment and for at least 12 weeks after treatment ends. Tell your doctor right away if you become pregnant during treatment. You should not breast-feed while you are using Zoladex.

You should not use Zoladex if you are allergic to goserelin or to similar hormone medications such as leuprolide (Lupron, Eligard, Viadur), nafarelin (Synarel), or ganirelix (Antagon).

Before you receive Zoladex, tell your doctor if you have osteoporosis, diabetes, urination problems, a condition affecting your spine, a history of heart attack or stroke, risk factors for coronary artery disease (such as high blood pressure, high cholesterol, smoking, or being overweight), or if you have abnormal bleeding that your doctor has not checked.

Zoladex can decrease bone mineral density, which may increase your risk of developing osteoporosis. This risk may be greater if you smoke, drink alcohol frequently, have a family history of osteoporosis, or use certain drugs such as seizure medications or steroids. Talk to your doctor about your individual risk of bone loss.

Call your doctor at once if you have a serious side effect while using Zoladex, such as severe numbness or tingling in your legs or feet, muscle weakness, problems with balance or coordination, loss of bladder or bowel control, urinating less than usual, pain or burning when you urinate, blood in your urine or stools, easy bruising, increased thirst or urination, fruity breath odor, trouble breathing, sudden numbness or weakness, sudden severe headache, confusion, problems with vision or speech, or chest pain spreading to the arm or shoulder

Before taking this medicine
You should not be treated with Zoladex implants if you are allergic to goserelin, or to similar hormone medications such as histrelin, leuprolide, nafarelin, or ganirelix.

This medicine can harm an unborn baby, but goserelin is sometimes used in pregnant women with advanced breast cancer. Unless you are being treated for advanced breast cancer, you should not use Zoladex during pregnancy. You may need to have a negative pregnancy test before starting this treatment.